Invention Grant
US08722655B2 Macrocyclic urea and sulfamide derivatives as inhibitors of tafia
有权
大环尿素和硫胺酰胺衍生物作为塔菲的抑制剂
- Patent Title: Macrocyclic urea and sulfamide derivatives as inhibitors of tafia
- Patent Title (中): 大环尿素和硫胺酰胺衍生物作为塔菲的抑制剂
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Application No.: US14048339Application Date: 2013-10-08
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Publication No.: US08722655B2Publication Date: 2014-05-13
- Inventor: Christopher Kallus , Mark Broenstrup , Andreas Evers , Anja Globisch , Herman Schreuder , Michael Wagner
- Applicant: Christopher Kallus , Mark Broenstrup , Andreas Evers , Anja Globisch , Herman Schreuder , Michael Wagner
- Applicant Address: FR Paris
- Assignee: Sanofi
- Current Assignee: Sanofi
- Current Assignee Address: FR Paris
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: EP08290520 20080606
- Main IPC: C07D413/14
- IPC: C07D413/14 ; C07D273/01 ; A61K31/553 ; A61P7/00

Abstract:
The invention relates to compounds of the formula (I) which are inhibitors of activated thrombin-activable fibrinolysis inhibitor. The compounds of the formula I are suitable for producing medicaments for prophylaxis, secondary prevention and treatment of one or more disorders associated with thromboses, embolisms, hypercoagulability or fibrotic changes.
Public/Granted literature
- US20140039011A1 MACROCYCLIC UREA AND SULFAMIDE DERIVATIVES AS INHIBITORS OF TAFIA Public/Granted day:2014-02-06
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