Invention Grant
- Patent Title: Hydroxamic acid derivatives useful as antibacterial agents
- Patent Title (中): 羟肟酸衍生物可用作抗菌剂
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Application No.: US13119484Application Date: 2009-09-01
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Publication No.: US08722686B2Publication Date: 2014-05-13
- Inventor: Matthew F. Brown , Charles F. Donovan , Edmund L. Ellsworth , Denton W. Hoyer , Timothy A. Johnson , Manjinder S. Lall , Chris Lim-Berakis , Sean T. Murphy , Debra A. Sherry , Clarke B. Taylor , Joseph S. Warmus
- Applicant: Matthew F. Brown , Charles F. Donovan , Edmund L. Ellsworth , Denton W. Hoyer , Timothy A. Johnson , Manjinder S. Lall , Chris Lim-Berakis , Sean T. Murphy , Debra A. Sherry , Clarke B. Taylor , Joseph S. Warmus
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Agent John A. Wichtowski
- International Application: PCT/IB2009/053809 WO 20090901
- International Announcement: WO2010/032147 WO 20100325
- Main IPC: A61K31/70
- IPC: A61K31/70 ; A61K31/67 ; A61K31/165 ; A61K31/415 ; A61K31/535 ; C07D239/42 ; C07D413/02 ; C07D239/02 ; C07D491/02 ; C07D213/56 ; C07D277/30 ; C07D261/06 ; C07D403/02 ; C07D233/54 ; C07D307/02 ; C07D235/02

Abstract:
The invention relates to a compound of formula (I): or a pharmaceutically acceptable salt thereof, thereof, wherein: G is a group of formula (II); and pharmaceutically acceptable salts, prodrugs, hydrates, or solvates, thereof, wherein A, B. L1-L4 A, B, R1-R4 and m are as defined herein. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and their use in treating a bacterial infection.
Public/Granted literature
- US20110178042A1 Hydroxamic Acid Derivatives Useful as Antibacterial Agents Public/Granted day:2011-07-21
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