Invention Grant
- Patent Title: Modulators of ATP-binding cassette-transporters
- Patent Title (中): ATP结合盒式转运蛋白的调节剂
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Application No.: US13936277Application Date: 2013-07-08
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Publication No.: US08722704B2Publication Date: 2014-05-13
- Inventor: Sara S. Hadida Ruah , Mark Miller , Jinglan Zhou , Brian Bear , Peter Grootenhuis
- Applicant: Vertex Pharmaceuticals Incorporated
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agent Susan C. Kelly
- Main IPC: C07D401/02
- IPC: C07D401/02 ; A61K31/47
Abstract:
Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
Public/Granted literature
- US20130296364A1 MODULATORS OF ATP-BINDING CASSETTE-TRANSPORTERS Public/Granted day:2013-11-07
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