Invention Grant
US08722742B2 Chemical compounds having antiviral activity against Dengue virus and other Flaviviruses
有权
对登革热病毒和其他黄病毒具有抗病毒活性的化合物
- Patent Title: Chemical compounds having antiviral activity against Dengue virus and other Flaviviruses
- Patent Title (中): 对登革热病毒和其他黄病毒具有抗病毒活性的化合物
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Application No.: US12919416Application Date: 2009-02-27
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Publication No.: US08722742B2Publication Date: 2014-05-13
- Inventor: Yuliet Mazola Reyes , Glay Chinea Santiago , Osmany Guirola Cruz , Roberto Vera Alvarez , Vivian Huerta Galindo , Noralvis Fleitas Salazar , Alexis Musacchio Lasa
- Applicant: Yuliet Mazola Reyes , Glay Chinea Santiago , Osmany Guirola Cruz , Roberto Vera Alvarez , Vivian Huerta Galindo , Noralvis Fleitas Salazar , Alexis Musacchio Lasa
- Applicant Address: CU Ciudad de la Habana
- Assignee: Centro de Ingenieria Genetica y Biotecnologia
- Current Assignee: Centro de Ingenieria Genetica y Biotecnologia
- Current Assignee Address: CU Ciudad de la Habana
- Agency: Hoffmann & Baron LLP
- Priority: CU2008-0028 20080229
- International Application: PCT/CU2009/000002 WO 20090227
- International Announcement: WO2009/106019 WO 20090903
- Main IPC: A01N41/06
- IPC: A01N41/06 ; A61K31/18 ; A61K31/535 ; A61K31/497 ; A61K31/4965 ; A01N43/40 ; A61K31/445
Abstract:
Use of chemical compounds obtained in silico for the preparation of pharmaceutical compositions to attenuate or inhibit Dengue virus infection. Particularly, through the interference or the modulation of several stages of viral replication cycle related with the entry of virus into host cells and the assembly of mature progeny virions. The invention also comprises the use of such pharmaceutical compositions for prophylactic and/or therapeutic treatment of infection caused by all four serotypes of Dengue virus and other flaviviruses.
Public/Granted literature
- US20110065686A1 CHEMICAL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST DENGUE VIRUS AND OTHER FLAVIVIRUSES Public/Granted day:2011-03-17
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