Invention Grant
- Patent Title: Gene therapy vectors and cytosine deaminases
- Patent Title (中): 基因治疗载体和胞嘧啶脱氨酶
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Application No.: US13072705Application Date: 2011-03-26
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Publication No.: US08722867B2Publication Date: 2014-05-13
- Inventor: Harry E. Gruber , Douglas J. Jolly , Omar D. Perez , Christopher R. Logg
- Applicant: Harry E. Gruber , Douglas J. Jolly , Omar D. Perez , Christopher R. Logg
- Applicant Address: US CA San Diego
- Assignee: Tocagen Inc.
- Current Assignee: Tocagen Inc.
- Current Assignee Address: US CA San Diego
- Agency: Gavrilovich, Dodd & Lindsey LLP
- Agent Joseph R. Baker, Jr.
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C07H21/00 ; C12N15/867 ; A61K35/76 ; C12N15/63

Abstract:
This disclosure provides modified cytosine deaminases (CDs). The disclosure further relates to cells and vector expressing or comprising such modified CDs and methods of using such modified CDs in the treatment of disease and disorders.
Public/Granted literature
- US20110217267A1 GENE THERAPY VECTORS AND CYTOSINE DEAMINASES Public/Granted day:2011-09-08
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