Invention Grant
- Patent Title: VMP-like sequences of pathogenic borrelia species and strains
- Patent Title (中): VMP样序列的致病性球孢子菌种和菌株
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Application No.: US13645950Application Date: 2012-10-05
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Publication No.: US08722871B2Publication Date: 2014-05-13
- Inventor: Steven J. Norris
- Applicant: Board of Regents, The University of Texas System
- Applicant Address: US TX Austin
- Assignee: Board of Regents, The University of Texas Systems
- Current Assignee: Board of Regents, The University of Texas Systems
- Current Assignee Address: US TX Austin
- Agency: Parker Highlander PLLC
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C07H21/02 ; A61K39/02
Abstract:
The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.
Public/Granted literature
- US20130102057A1 VMP-LIKE SEQUENCES OF PATHOGENIC BORRELIA SPECIES AND STRAINS Public/Granted day:2013-04-25
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