Invention Grant
- Patent Title: Pyrimidine derivatives for the treatment of abnormal cell growth
- Patent Title (中): 嘧啶衍生物用于治疗异常细胞生长
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Application No.: US12095716Application Date: 2006-11-20
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Publication No.: US08722884B2Publication Date: 2014-05-13
- Inventor: John Charles Kath , Michael Joseph Luzzio , Susan La Greca , Nandini Chaturbhai Patel
- Applicant: John Charles Kath , Michael Joseph Luzzio , Susan La Greca , Nandini Chaturbhai Patel
- Applicant Address: US MA Cambridge
- Assignee: Verastem, Inc.
- Current Assignee: Verastem, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Lando & Anastasi LLP
- International Application: PCT/IB2006/003349 WO 20061120
- International Announcement: WO2007/063384 WO 20070607
- Main IPC: C07D403/12
- IPC: C07D403/12 ; A61K31/505
Abstract:
The present invention relates to salts, solvates and substoichiometric solvates of N-[3-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methylmethanesulfonamide. The invention also provides pharmaceutical compositions comprising such complexes, as well as methods of treating abnormal cell growth by administering the complexes of the invention.
Public/Granted literature
- US20110033441A1 PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH Public/Granted day:2011-02-10
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