Invention Grant
US08722890B2 Thieno[3,2-C]pyridine kinase inhibitors with improved CYP safety profile
有权
噻吩并[3,2-C]吡啶激酶抑制剂，具有改善的CYP安全性
![Thieno[3,2-C]pyridine kinase inhibitors with improved CYP safety profile](/docs/US/2014-05-13/US08722890B2/abs.jpg.600x600.jpg)
- Patent Title: Thieno[3,2-C]pyridine kinase inhibitors with improved CYP safety profile
- Patent Title (中): 噻吩并[3,2-C]吡啶激酶抑制剂，具有改善的CYP安全性
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Application No.: US13585333Application Date: 2012-08-14
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Publication No.: US08722890B2Publication Date: 2014-05-13
- Inventor: Michael R. Michaelides , Robin Frey , Michael Curtin
- Applicant: Michael R. Michaelides , Robin Frey , Michael Curtin
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Agency: Michael Best & Friedrich LLP
- Agent Lisa V. Mueller
- Main IPC: C07D495/04
- IPC: C07D495/04 ; A61K31/4365
![Thieno[3,2-C]pyridine kinase inhibitors with improved CYP safety profile](/abs-image/US/2014/05/13/US08722890B2/abs.jpg.150x150.jpg)
Abstract:
Compounds that inhibit protein kinases such as Aurora-kinases and the VEGFR and PDGFR families of kinases, with an improved safety profile due to low CYP3A4 inhibition, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.
Public/Granted literature
- US20120309783A1 KINASE INHIBITORS WITH IMPROVED CYP SAFETY PROFILE Public/Granted day:2012-12-06
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