Invention Grant
- Patent Title: Protease inhibitors
- Patent Title (中): 蛋白酶抑制剂
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Application No.: US13321078Application Date: 2010-05-18
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Publication No.: US08722930B2Publication Date: 2014-05-13
- Inventor: Rajeev Goswami , Anil Kumar Vuppala , Ramesh Veludandi , Ramesh Sistla , Chakshusmathi Ghadiyaram , Muralidhara Ramachandra
- Applicant: Rajeev Goswami , Anil Kumar Vuppala , Ramesh Veludandi , Ramesh Sistla , Chakshusmathi Ghadiyaram , Muralidhara Ramachandra
- Applicant Address: FI Espoo
- Assignee: Orion Corporation
- Current Assignee: Orion Corporation
- Current Assignee Address: FI Espoo
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Priority: IN758/KOL/2009 20090518
- International Application: PCT/FI2010/000031 WO 20100518
- International Announcement: WO2010/133748 WO 20101125
- Main IPC: C07C233/65
- IPC: C07C233/65 ; A61K31/165

Abstract:
A compound of formula (I) wherein R1 to R15, P1, P2, A, B and Q are as defined in the claims and pharmaceutically acceptable salts and esters thereof, are disclosed. The compounds of formula (I) possess utility as matriptase inhibitors and are useful in the treatment of matriptase dependent conditions, particularly cancer.
Public/Granted literature
- US20120136002A1 PROTEASE INHIBITORS Public/Granted day:2012-05-31
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