Invention Grant
- Patent Title: Method for producing biphenyl derivative
- Patent Title (中): 联苯衍生物的制备方法
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Application No.: US12377892Application Date: 2007-10-12
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Publication No.: US08722942B2Publication Date: 2014-05-13
- Inventor: Tamio Hayashi , Jiro Nakatani
- Applicant: Tamio Hayashi , Jiro Nakatani
- Applicant Address: JP
- Assignee: Toray Fine Chemicals Co., Ltd.
- Current Assignee: Toray Fine Chemicals Co., Ltd.
- Current Assignee Address: JP
- Agency: DLA Piper LLP (US)
- Priority: JP2006-281677 20061016
- International Application: PCT/JP2007/069957 WO 20071012
- International Announcement: WO2008/047707 WO 20080424
- Main IPC: C07C43/164
- IPC: C07C43/164 ; C07C17/269 ; C07C2/84 ; C07C43/205 ; C07C17/263

Abstract:
A method produces a biphenyl derivative, with an industrially high yield and excellent productivity, by use of a raw material which is low in cost and toxicity. The method for producing the biphenyl derivative represented by Formula (1) is characterized in that a chlorine atom in a benzene derivative represented by Formula (2) reacts with magnesium metal to convert the benzene derivative into a Grignard reagent, and then the Grignard reagent is subjected to a coupling reaction in the presence of a catalyst and a dichloropropane: (wherein A represents at least one selected from alkyl groups, alkoxy groups, alkoxymethyl groups, a vinyl group, phenyl groups and chlorine, and n represents an integer of 1 to 4).
Public/Granted literature
- US20100230634A1 METHOD FOR PRODUCING BIPHENYL DERIVATIVE Public/Granted day:2010-09-16
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