An electromagnetically shielded enclosure with operable interfaces that is portable and lightweight. The electromagnetically shielded enclosure has operable interfaces including a tactile interface through the shielding material and optionally a shielded tactile window for viewing of a secured electronic device and also for operating the secured electronic device should it have a touch screen. An internal frame is optionally provided that prevents conductive interference of a secured electronic device touch screen by the shielded tactile window. An input/output assembly is further provided to allow signals and power to be brought in or out of the enclosure to connect with the secured electronic device without compromising radio silence.