A method for binding input/output (I/O) objects to nodes includes an subsystem receiving a request to use an I/O device from a process, determining a first resource to service the request, generating a first I/O object corresponding to the first resource, wherein the first I/O object is unbound, and sending the first I/O object to a Non-Uniform Memory Access (NUMA) I/O Framework. The method further includes the NUMA I/O Framework selecting a first NUMA node of a plurality of NUMA nodes, to which to bind the first I/O object and binding the first I/O object to the first NUMA node. The method further includes servicing the request by processing, on the first NUMA node, the first resource corresponding to the first I/O object.