A method for distributed diagnostic reasoning is provided. The method includes establishing a computing node monitoring the operation of a component of a complex system and populating at least one of a processor and the memory of the computing node with one or more standardized executable application modules (SEAMs) and a workflow service. The method further includes creating a configuration file in combination with several SEAMS to create a distributed diagnostic reasoner (DDR) associated with the component. The method also comprises installing the configuration file in the computing node for execution by the processor; and initializing the one or more SEAMS, the configuration file and the workflow service, wherein the workflow service facilitates data flow between the one or more SEAMS and the static data associated with a fault condition resident in the configuration file.