Provided is an interchangeable makeup brush including: a plurality of brush tips fixing a brush; and a brush rod having the brush tip detachably coupled thereto, and being grasped by a hand of a user, wherein the brush tip includes a mounting protruding portion formed at a rear thereof which is inserted and coupled in the brush rod. According to the present invention, a brush tip may be attached and detached to and from a brush rod, enabling convenient use when applying makeup by selecting and mounting a required brush, and allowing only one brush rod to be provided for economical advantage and ease of portability and storage.