An air filter cartridge arrangement, an air cleaner assembly, and components therefor, are provided. The air filter cartridge generally has perimeter shape with a straight side and an opposite arched side. The filter cartridge includes a media pack comprising strips of single facer material, each strip comprising fluted sheet secured to a facing sheet. In an example depicted, arch-shaped sections of single facer material are nested within one another, to form media pack having a perimeter D-shape. An air cleaner assembly configured for receipt of filter cartridge is described. A particular assembly, convenient for mounting on the cowl, cowling or engine cover of an over-the-highway truck, is provided.