Invention Grant
- Patent Title: Compositions and methods to enhance the immune system
- Patent Title (中): 组合和增强免疫系统的方法
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Application No.: US12937764Application Date: 2009-04-23
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Publication No.: US08728476B2Publication Date: 2014-05-20
- Inventor: Timo Kars van den Berg
- Applicant: Timo Kars van den Berg
- Applicant Address: NL Amsterdam
- Assignee: Stichting Sanquin Bloedvoorziening
- Current Assignee: Stichting Sanquin Bloedvoorziening
- Current Assignee Address: NL Amsterdam
- Agency: Hoffman & Baron LLP
- Priority: EP08155011 20080423
- International Application: PCT/NL2009/050220 WO 20090423
- International Announcement: WO2009/131453 WO 20091029
- Main IPC: A61K31/395
- IPC: A61K31/395 ; A61K38/00
Abstract:
The invention relates to the field of molecular medicine. In particular, it relates to compositions and methods to enhance the clearance of aberrant cells, e.g. cancer cells or virus-infected cells, by the host's immune system. Provided is a composition comprising (i) a therapeutic compound that can trigger a host's immune effector cells against an aberrant cell, such as a therapeutic antibody, and (ii) at least one agent capable of reducing or preventing inhibitory signal transduction initiated via SIRPalpha.
Public/Granted literature
- US20110038870A1 COMPOSITIONS AND METHODS TO ENHANCE THE IMMUNE SYSTEM Public/Granted day:2011-02-17
Information query
