Invention Grant
- Patent Title: Malaria vaccine compositions and constituents which elicit cell mediated immunity
- Patent Title (中): 引起细胞介导免疫的疟疾疫苗组合物和成分
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Application No.: US12863040Application Date: 2009-01-12
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Publication No.: US08728492B2Publication Date: 2014-05-20
- Inventor: Avigdor Shafferman , Anat Zvi , John Fulkerson , Jerald C. Sadoff
- Applicant: Avigdor Shafferman , Anat Zvi , John Fulkerson , Jerald C. Sadoff
- Applicant Address: US MD Rockville
- Assignee: Aeras Global TB Vaccine Foundation
- Current Assignee: Aeras Global TB Vaccine Foundation
- Current Assignee Address: US MD Rockville
- Agency: Pepper Hamilton, LLP
- International Application: PCT/US2009/030734 WO 20090112
- International Announcement: WO2009/091692 WO 20090723
- Main IPC: A61K39/015
- IPC: A61K39/015 ; A61K49/00 ; C07H21/04
Abstract:
Malaria vaccines based on polyepitope constructs that elicit cell-mediated immunity against a broad spectrum of malaria parasites and which cover the majority of HLA alleles are provided. Epitopes in the polyepitope constructs are from regions of the Plasmodium falciparum circumsporozoite protein (CSP) known to contain CD4 and CD8 T cell epitopes, and include both epitopes from highly variable and highly conserved regions of CSP.
Public/Granted literature
- US20110206714A1 MALARIA VACCINE COMPOSITIONS AND CONSTITUENTS WHICH ELICIT CELL MEDIATED IMMUNITY Public/Granted day:2011-08-25
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