Invention Grant
US08728740B2 Monoclonal antibody and its use for the identification of the oncofetal isoform of fibronectin (B-FN) for diagnosis or therapy
有权
单克隆抗体及其用于鉴定纤维连接蛋白（B-FN）的支原体异构体用于诊断或治疗
- Patent Title: Monoclonal antibody and its use for the identification of the oncofetal isoform of fibronectin (B-FN) for diagnosis or therapy
- Patent Title (中): 单克隆抗体及其用于鉴定纤维连接蛋白（B-FN）的支原体异构体用于诊断或治疗
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Application No.: US13139112Application Date: 2009-12-11
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Publication No.: US08728740B2Publication Date: 2014-05-20
- Inventor: Patrizia Castellani , Francesca Sassi , M. Barbara Carnemolla , Laura Borsi , Enrica Balza
- Applicant: Patrizia Castellani , Francesca Sassi , M. Barbara Carnemolla , Laura Borsi , Enrica Balza
- Applicant Address: IT Genoa
- Assignee: Sirius-Biotech S.R.L.
- Current Assignee: Sirius-Biotech S.R.L.
- Current Assignee Address: IT Genoa
- Agency: Abelman, Frayne & Schwab
- Priority: ITFI2008A000240 20081212
- International Application: PCT/EP2009/066907 WO 20091211
- International Announcement: WO2010/066872 WO 20100617
- Main IPC: G01N33/53
- IPC: G01N33/53
Abstract:
Epitopes localized on FNIII-8 repeat that are normally cryptic but are unmasked by insertion of FNIII-B into the FN molecule and are recognized by specific ligands are described; antibodies or their fragments able to identify the above said epitope are also described.
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