Invention Grant
US08728750B2 Process for preparation of optically active N-protected 3-aminopyrrolidine or optically active N-protected 3-aminopiperidine and the corresponding ketones by optical resolution of the racemic amine mixtures employing a bacterial omega-transaminase
有权
通过旋光拆分外消旋胺混合物制备光学活性N-保护的3-氨基吡咯烷或光学活性N-保护的3-氨基哌啶和相应的酮的方法，其使用细菌ω-转氨酶
- Patent Title: Process for preparation of optically active N-protected 3-aminopyrrolidine or optically active N-protected 3-aminopiperidine and the corresponding ketones by optical resolution of the racemic amine mixtures employing a bacterial omega-transaminase
- Patent Title (中): 通过旋光拆分外消旋胺混合物制备光学活性N-保护的3-氨基吡咯烷或光学活性N-保护的3-氨基哌啶和相应的酮的方法，其使用细菌ω-转氨酶
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Application No.: US12438674Application Date: 2007-09-06
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Publication No.: US08728750B2Publication Date: 2014-05-20
- Inventor: Karen Robins , Uwe Bornscheuer , Matthias Höhne
- Applicant: Karen Robins , Uwe Bornscheuer , Matthias Höhne
- Applicant Address: CH Visp
- Assignee: Lonza AG
- Current Assignee: Lonza AG
- Current Assignee Address: CH Visp
- Agency: Harness, Dickey & Pierce, P.L.C.
- Priority: EP06018637 20060906
- International Application: PCT/EP2007/007770 WO 20070906
- International Announcement: WO2008/028654 WO 20080313
- Main IPC: C12Q1/52
- IPC: C12Q1/52 ; C12P1/00
Abstract:
The present invention relates to the production of optically active amines, which can be used as intermediate products in a synthesis of for instance pharmaceutical products.
Public/Granted literature
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