Invention Grant
US08728756B2 Promoting axon regeneration in the adult CNS through control of protein translation
有权
通过控制蛋白质翻译促进成人CNS中的轴突再生
- Patent Title: Promoting axon regeneration in the adult CNS through control of protein translation
- Patent Title (中): 通过控制蛋白质翻译促进成人CNS中的轴突再生
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Application No.: US13729091Application Date: 2012-12-28
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Publication No.: US08728756B2Publication Date: 2014-05-20
- Inventor: Zhigang He , Kevin Park , Kai Liu , Yang Hu
- Applicant: Children's Medical Center Corporation
- Applicant Address: US MA Boston
- Assignee: Children's Medical Center Corporation
- Current Assignee: Children's Medical Center Corporation
- Current Assignee Address: US MA Boston
- Agency: Nixon Peabody LLP
- Agent David S. Resnick; Shayne Y. Huff
- Main IPC: C12Q1/02
- IPC: C12Q1/02 ; A61K49/00
Abstract:
Survival of, or axon regeneration in a lesioned mature central nervous system (CNS) neuron is promoted by (a) contacting the neuron with a therapeutically effective amount of an exogenous activator of protein translation; and (b) detecting the resultant promotion of the survival of, or axon regeneration in the neuron.
Public/Granted literature
- US20130123228A1 PROMOTING AXON REGENERATION IN THE ADULT CNS THROUGH CONTROL OF PROTEIN TRANSLATION Public/Granted day:2013-05-16
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