Invention Grant
- Patent Title: Methods of expanding and redifferentiating islet beta cells
- Patent Title (中): 扩增和再分化胰岛β细胞的方法
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Application No.: US13338453Application Date: 2011-12-28
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Publication No.: US08728813B2Publication Date: 2014-05-20
- Inventor: Shimon Efrat , Yael Bar , Holger A. Russ
- Applicant: Shimon Efrat , Yael Bar , Holger A. Russ
- Applicant Address: IL Tel-Aviv
- Assignee: Ramot at Tel-Aviv University Ltd.
- Current Assignee: Ramot at Tel-Aviv University Ltd.
- Current Assignee Address: IL Tel-Aviv
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/02 ; C12N15/00 ; A61K38/00 ; C12N15/11 ; A61K48/00

Abstract:
A method of ex-vivo increasing insulin content in progenitor cells which express SLUG is provided. The method comprises downregulating an amount or activity of SLUG in the progenitor cells. Cell populations generated thereby and uses thereof are also provided.
Public/Granted literature
- US20120121560A1 METHODS OF EXPANDING AND REDIFFERENTIATING ISLET BETA CELLS Public/Granted day:2012-05-17
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