Invention Grant
US08728816B2 Production of glycoproteins with low N-glycolylneuraminic acid (NEU5GC) content 有权
生产低N-羟乙酰神经氨酸(NEU5GC)含量的糖蛋白

  • Patent Title: Production of glycoproteins with low N-glycolylneuraminic acid (NEU5GC) content
  • Patent Title (中): 生产低N-羟乙酰神经氨酸(NEU5GC)含量的糖蛋白
  • Application No.: US13503254
    Application Date: 2010-11-19
  • Publication No.: US08728816B2
    Publication Date: 2014-05-20
  • Inventor: Tanja Ficko Trcek
  • Applicant: Tanja Ficko Trcek
  • Applicant Address: SI Liubliana
  • Assignee: Lek Pharmaceuticals D.D.
  • Current Assignee: Lek Pharmaceuticals D.D.
  • Current Assignee Address: SI Liubliana
  • Agency: Parker Highlander PLLC
  • Priority: EP09176631 20091120
  • International Application: PCT/EP2010/067793 WO 20101119
  • International Announcement: WO2011/061275 WO 20110526
  • Main IPC: C12N5/00
  • IPC: C12N5/00
Production of glycoproteins with low N-glycolylneuraminic acid (NEU5GC) content
Abstract:
The present invention relates to a medium for the cultivation of eukaryotic cells, the medium comprising as (an) additive(s) DMSO, N-acetylmannosamine (NAcMan), N-acetylglucosamine (NAcGlc), or any combination of two or more of these additives, including the combination of NAcMan and NAcGlc.
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