Invention Grant
US08728817B2 Compositions and methods for making and using laminin nanofibers
有权
制备和使用层粘连蛋白纳米纤维的组合物和方法
- Patent Title: Compositions and methods for making and using laminin nanofibers
- Patent Title (中): 制备和使用层粘连蛋白纳米纤维的组合物和方法
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Application No.: US13045095Application Date: 2011-03-10
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Publication No.: US08728817B2Publication Date: 2014-05-20
- Inventor: Roy Clinton Ogle , Edward A. Botchwey, III , Rebekah A. Neal
- Applicant: Roy Clinton Ogle , Edward A. Botchwey, III , Rebekah A. Neal
- Applicant Address: US VA Charlottesville
- Assignee: University of Virginia Patent Foundation
- Current Assignee: University of Virginia Patent Foundation
- Current Assignee Address: US VA Charlottesville
- Agent Rodney L. Sparks
- Main IPC: C12N5/0793
- IPC: C12N5/0793 ; C07K14/00
Abstract:
The present invention provides methodologies and parameters for fabrication of the hybrid biomaterial by blending pure laminin or complex extracts of tissues containing laminin with biopolymers such as polycaprolactone (PCL), polylactic/polyglycolic acid copolymer (PLGA) or Polydioxanone (PDO) in fluoroalcohols (HFP, TFA), fabrication of substrates and scaffolds and devices from the hybrid biomaterial in forms such as films, nanofibers by electrospinning or microspheres, and the biological or biomedical use of the material or devices derived from it.
Public/Granted literature
- US20110236974A1 COMPOSITIONS AND METHODS FOR MAKING AND USING LAMININ NANOFIBERS Public/Granted day:2011-09-29
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