Invention Grant
US08729029B2 Peptide derivatives and use thereof as carriers for molecules in the form of conjugates
有权
肽衍生物及其作为缀合物形式的分子的载体的用途
- Patent Title: Peptide derivatives and use thereof as carriers for molecules in the form of conjugates
- Patent Title (中): 肽衍生物及其作为缀合物形式的分子的载体的用途
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Application No.: US13125634Application Date: 2009-10-20
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Publication No.: US08729029B2Publication Date: 2014-05-20
- Inventor: Michel Khrestchatisky , Marion David , Yves Molino , Patrick Vlieghe
- Applicant: Michel Khrestchatisky , Marion David , Yves Molino , Patrick Vlieghe
- Applicant Address: FR Marseilles FR Paris FR Marseilles
- Assignee: Vect-Horus,Centre National de la Recherche Scientifique,Universite d'Aix-Marseille
- Current Assignee: Vect-Horus,Centre National de la Recherche Scientifique,Universite d'Aix-Marseille
- Current Assignee Address: FR Marseilles FR Paris FR Marseilles
- Agency: Saliwanchik, Lloyd & Eisenschenk
- Priority: FR0857159 20081022
- International Application: PCT/FR2009/051991 WO 20091020
- International Announcement: WO2010/046588 WO 20100429
- Main IPC: A61K38/16
- IPC: A61K38/16 ; C07K4/00 ; C07K7/50
Abstract:
The invention relates to peptide derivatives (peptides and pseudo-peptides) and use thereof as vectors for molecules of interest. The invention also relates to conjugates containing a peptide derivative of the invention bound to a molecule of interest. The peptides and prodrug conjugates of the invention can be used to vectorise molecules of pharmaceutical or diagnostic interest, such as, for example, therapeutic molecules, imaging or diagnostic agents, or molecular probes, across cell membranes, and notably to promote their transport across the blood-brain barrier (BBB).
Public/Granted literature
- US20110230416A1 PEPTIDE DERIVATIVES AND USE THEREOF AS CARRIERS FOR MOLECULES IN THE FORM OF CONJUGATES Public/Granted day:2011-09-22
Information query
IPC分类:
