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Invention Grant
US08729035B2 Synthesis of novel neamine derivatives and use thereof as antibacterial agents 有权
新型神经胺衍生物的合成及其作为抗菌剂的用途

Synthesis of novel neamine derivatives and use thereof as antibacterial agents
Abstract:
This invention concerns compounds with the formula: in which: R1═OH or NH2; OR2, OR3, OR4 and OR5 are alcohol, ether, ester, carbonate, carbamate, sulphonate or sulphamate groups; and if R5═H if R2═R3═R4, then R2, R3 and R4≠H; if R2═H, then R3≠H and R4≠H; if R3═H, then R2≠H and R4≠H; if R4═H, then R2≠H and R3≠H; if R5≠H if R2=H, then R3≠H and R4≠H; if R3═H, then R2≠H and R4≠H; if R4═H, then R2≠H and R3≠H, their use as antibiotic agents and the process for synthesizing them.
Abstract(Chinese):

本发明涉及下式的化合物：其中：R1 = OH或NH2; OR2，OR3，OR4和OR5是醇，醚，酯，碳酸酯，氨基甲酸酯，磺酸酯或氨基磺酸酯基团; 如果R 2 = R 3 = R 4，如果R 5为H，那么R 2，R 3和R 4≠H; 如果R2 = H，则R3≠H，R4≠H; 如果R3 = H，则R2≠H，R4≠H; 如果R4 = H，则R2≠H，R3≠H; 如果R2 = H，则R5≠H，则R3≠H，R4≠H; 如果R3 = H，则R2≠H，R4≠H; 如果R4 = H，那么R2≠H，R3≠H，它们作为抗生素的用途和合成方法。

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