Invention Grant
US08729037B2 Method and medicament for inhibiting the expression of a given gene
有权
用于抑制给定基因表达的方法和药物
- Patent Title: Method and medicament for inhibiting the expression of a given gene
- Patent Title (中): 用于抑制给定基因表达的方法和药物
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Application No.: US11982345Application Date: 2007-10-31
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Publication No.: US08729037B2Publication Date: 2014-05-20
- Inventor: Roland Kreutzer , Stefan Limmer
- Applicant: Roland Kreutzer , Stefan Limmer
- Applicant Address: US MA Cambridge
- Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Fenwick & West LLP
- Priority: DE19903713 19990130; DE19956568 19991124
- Main IPC: C12N15/113
- IPC: C12N15/113
Abstract:
The present invention relates to the specific inhibition of expression of a target gene in mammals using a short double stranded RNA. The dsRNA is less than 49 nucleotides in length and has a nucleotide sequence which is complementary to at least a part of the target gene. The dsRNAs of the present invention are useful for treating diseases, for example, cancer, viral diseases or neurodegenerative diseases.
Public/Granted literature
- US20080261303A1 Method and medicament for inhibiting the expression of a given gene Public/Granted day:2008-10-23
Information query
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