Invention Grant
US08729050B2 Method for prevention and treatment of reflux injury in the aerodigestive tract and laryngopharynx caused by pepsin
有权
预防和治疗由胃蛋白酶引起的呼吸消化道和咽喉反流性损伤的方法
- Patent Title: Method for prevention and treatment of reflux injury in the aerodigestive tract and laryngopharynx caused by pepsin
- Patent Title (中): 预防和治疗由胃蛋白酶引起的呼吸消化道和咽喉反流性损伤的方法
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Application No.: US12575366Application Date: 2009-10-07
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Publication No.: US08729050B2Publication Date: 2014-05-20
- Inventor: Jamie Koufman , Michael James , Peter Josling
- Applicant: Jamie Koufman , Michael James , Peter Josling
- Applicant Address: GB
- Assignee: Euphora Ltd.
- Current Assignee: Euphora Ltd.
- Current Assignee Address: GB
- Agency: Ostrolenk Faber LLP
- Main IPC: A61K31/717
- IPC: A61K31/717 ; A61K31/715 ; A61K9/14

Abstract:
A method for treating or preventing disorders, diseases, and symptom of reflux, that is laryngopharyngeal reflux (LPR), in the laryngopharynx caused by pepsin comprises orally administering to the laryngopharynx of a patient an effective amount of cellulose powder. A method for treating or preventing damage to the lining membranes of at least some of the aerodigestive tract, the damage caused by pepsin, comprises coating at least some of the lining membranes with an effective amount of a cellulose powder. Upon inhalation of the powder, the powder coats the lining membranes. Upon coating the lining membranes, the powder becomes a gel. The gel prevents the pepsin from binding with the lining membranes, thereby preventing damage caused by pepsin in laryngopharyngeal reflux or in extra-esophageal reflux.
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