Invention Grant
US08729073B2 5-methyl-1-(naphthalen-2-yl)-1H-pyrazole derivatives and their use in potentiating the effect of opioid analgesics
有权
5-甲基-1-(萘-2-基)-1H-吡唑衍生物及其用于增强阿片类镇痛药的作用
- Patent Title: 5-methyl-1-(naphthalen-2-yl)-1H-pyrazole derivatives and their use in potentiating the effect of opioid analgesics
- Patent Title (中): 5-甲基-1-(萘-2-基)-1H-吡唑衍生物及其用于增强阿片类镇痛药的作用
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Application No.: US13991267Application Date: 2011-12-02
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Publication No.: US08729073B2Publication Date: 2014-05-20
- Inventor: Antoni Torrens Jover , María Rosa Cuberes-Altisent
- Applicant: Antoni Torrens Jover , María Rosa Cuberes-Altisent
- Applicant Address: ES Barcelona
- Assignee: Laboratorios Del Dr. Esteve, S.A.
- Current Assignee: Laboratorios Del Dr. Esteve, S.A.
- Current Assignee Address: ES Barcelona
- Agency: Cooper & Dunham LLP
- Agent Gary J. Gershik
- Priority: EP10382326 20101203
- International Application: PCT/EP2011/071583 WO 20111202
- International Announcement: WO2012/072781 WO 20120607
- Main IPC: A61K31/535
- IPC: A61K31/535 ; A61K31/44 ; C07D265/30

Abstract:
The invention relates to pyrazole derivatives of formula I having pharmacological activity and to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy and/or prophylaxis of pain.
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