Invention Grant
- Patent Title: Secondary 8-hydroxyquinoline-7-carboxamide derivatives
- Patent Title (中): 次级8-羟基喹啉-7-甲酰胺衍生物
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Application No.: US13519686Application Date: 2010-12-28
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Publication No.: US08729076B2Publication Date: 2014-05-20
- Inventor: Stefania Gagliardi , Simone Del Sordo , Federico Mailland , Michela Legora
- Applicant: Stefania Gagliardi , Simone Del Sordo , Federico Mailland , Michela Legora
- Applicant Address: LU Luxembourg
- Assignee: Polichem SA
- Current Assignee: Polichem SA
- Current Assignee Address: LU Luxembourg
- Agency: Hueschen and Sage
- Priority: EP09180895 20091229
- International Application: PCT/EP2010/070793 WO 20101228
- International Announcement: WO2011/080266 WO 20110707
- Main IPC: A61K31/5377
- IPC: A61K31/5377 ; A61K31/497 ; A61K31/47 ; C07D403/02 ; C07D413/02 ; C07D215/00
Abstract:
The present invention provides new secondary 8-hydroxyquinoline-7-carboxamide derivatives of general formula (I) and pharmaceutically acceptable salts thereof. These compounds are useful as antifungal agents. Specifically, these compounds were tested against Tricophyton Rubrum, Tricophyton Mentagrophytes, Aspergillus Niger and Scopulariopsis Brevicaulis. Many of these compounds are active against Candida species such as Candida Albicans and Candida Glabrata.
Public/Granted literature
- US20120316167A1 SECONDARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES Public/Granted day:2012-12-13
Information query
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