Invention Grant
- Patent Title: Benzofuranyl analogues as GPR119 modulators
- Patent Title (中): 苯并呋喃基类似物作为GPR119调节剂
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Application No.: US13696131Application Date: 2011-05-04
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Publication No.: US08729084B2Publication Date: 2014-05-20
- Inventor: Xiang-Yang Ye , Dean A. Wacker , Jeffrey A. Robl
- Applicant: Xiang-Yang Ye , Dean A. Wacker , Jeffrey A. Robl
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- International Application: PCT/US2011/035087 WO 20110504
- International Announcement: WO2011/140161 WO 20111110
- Main IPC: C07D405/14
- IPC: C07D405/14 ; A61K31/506

Abstract:
Novel compounds of structure Formula I: or an enantiomer, diastereomer, tautomer, prodrug or salt thereof, wherein A, L, m, n, o, p, R2, R3, R3, R4 and R5 are defined herein, are provided which are GPR119 G protein-coupled receptor modulators. GPR119 G protein-coupled receptor modulators are useful in treating, preventing, or slowing the progression of diseases requiring GPR119 G protein-coupled receptor modulator therapy. Thus, the disclosure also concerns compositions comprising these novel compounds and methods of treating diseases or conditions related to the activity of the GPR119 G protein-coupled receptor by using any of these novel compounds or a composition comprising any of such novel compounds.
Public/Granted literature
- US20130059858A1 BENZOFURANYL ANALOGUES AS GPR119 MODULATORS Public/Granted day:2013-03-07
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