Invention Grant
US08729091B2 4-phenoxy-nicotinamide or 4-phenoxy-pyrimidine-5-carboxamide compounds
有权
4-苯氧基 - 烟酰胺或4-苯氧基 - 嘧啶-5-甲酰胺化合物
- Patent Title: 4-phenoxy-nicotinamide or 4-phenoxy-pyrimidine-5-carboxamide compounds
- Patent Title (中): 4-苯氧基 - 烟酰胺或4-苯氧基 - 嘧啶-5-甲酰胺化合物
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Application No.: US13767907Application Date: 2013-02-15
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Publication No.: US08729091B2Publication Date: 2014-05-20
- Inventor: Caterina Bissantz , Henrietta Dehmlow , Shawn David Erickson , Kyungjin Kim , Rainer E. Martin , Ulrike Obst Sander , Sherrie Lynn Pietranico-Cole , Hans Richter , Christoph Ullmer
- Applicant: Hoffmann-La Roche Inc.
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Priority: EP10151319 20100121
- Main IPC: A61K31/505
- IPC: A61K31/505 ; A61K31/4427

Abstract:
This invention relates to novel phenyl amide or pyridyl amide derivatives of the formula wherein A1, A2, B1, B2 and R1 to R11 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and can be used as medicaments for the treatment of diseases such as type II diabetes.
Public/Granted literature
- US20130150372A1 4-PHENOXY-NICOTINAMIDE OR 4-PHENOXY-PYRIMIDINE-5-CARBOXAMIDE COMPOUNDS Public/Granted day:2013-06-13
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