Invention Grant
US08729097B2 Quinoline compounds as inhibitors of angiogenesis, human methionine aminopeptidase, and SIRT1, and methods of treating disorders
有权
作为血管生成抑制剂的喹啉化合物，人甲硫氨酸氨基肽酶和SIRT1，以及治疗疾病的方法
- Patent Title: Quinoline compounds as inhibitors of angiogenesis, human methionine aminopeptidase, and SIRT1, and methods of treating disorders
- Patent Title (中): 作为血管生成抑制剂的喹啉化合物，人甲硫氨酸氨基肽酶和SIRT1，以及治疗疾病的方法
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Application No.: US13122876Application Date: 2009-10-06
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Publication No.: US08729097B2Publication Date: 2014-05-20
- Inventor: Jun O. Liu , Joong Sup Shim , Curtis R. Chong , Shridhar Bhat
- Applicant: Jun O. Liu , Joong Sup Shim , Curtis R. Chong , Shridhar Bhat
- Applicant Address: US MD Baltimore
- Assignee: The Johns Hopkins University
- Current Assignee: The Johns Hopkins University
- Current Assignee Address: US MD Baltimore
- Agency: Edwards Wildman Palmer LLP
- Agent Peter F. Corless
- International Application: PCT/US2009/005475 WO 20091006
- International Announcement: WO2010/042163 WO 20100415
- Main IPC: A61K31/04
- IPC: A61K31/04
Abstract:
Described herein are methods of inhibiting methionine aminopeptidase or SirT1, inhibiting angiogenesis, and treating disorders (or symptoms thereof) associated with methionine aminopeptidase, SirT1 and/or angiogenesis, wherein a compound of the invention is administered to a subject.
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