Invention Grant
US08729103B2 Silent desensitizers of neuronal nAChR and methods of use thereof
有权
神经元nAChR的沉默脱敏剂及其使用方法
- Patent Title: Silent desensitizers of neuronal nAChR and methods of use thereof
- Patent Title (中): 神经元nAChR的沉默脱敏剂及其使用方法
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Application No.: US12994376Application Date: 2009-05-26
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Publication No.: US08729103B2Publication Date: 2014-05-20
- Inventor: Milton L. Brown , Mikell A. Paige , Yingxian Xiao , Kenneth J. Kellar
- Applicant: Milton L. Brown , Mikell A. Paige , Yingxian Xiao , Kenneth J. Kellar
- Applicant Address: US DC Washington
- Assignee: Georgetown University
- Current Assignee: Georgetown University
- Current Assignee Address: US DC Washington
- Agency: Foley Hoag LLP
- Agent Dana M. Gordon
- International Application: PCT/US2009/045136 WO 20090526
- International Announcement: WO2009/143507 WO 20091126
- Main IPC: A61K31/4439
- IPC: A61K31/4439 ; C07D401/14
Abstract:
One aspect of the present invention relates to heterocyclic compounds that are ligands for nicotinic acetylcholine receptors. A second aspect of the invention relates to the use of a compound of the invention for modulation of a mammalian nicotinic acetylcholine receptor.
Public/Granted literature
- US20110269733A1 Silent Desensitizers of Neuronal nAChR and Methods of Use Thereof Public/Granted day:2011-11-03
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