Invention Grant
US08729114B2 Heteroaryl nitrile compounds useful as inhibitors of Cathepsin-S
有权
可用作组织蛋白酶-S抑制剂的杂芳基腈化合物
- Patent Title: Heteroaryl nitrile compounds useful as inhibitors of Cathepsin-S
- Patent Title (中): 可用作组织蛋白酶-S抑制剂的杂芳基腈化合物
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Application No.: US13581829Application Date: 2011-03-02
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Publication No.: US08729114B2Publication Date: 2014-05-20
- Inventor: Michael J. Burke , Derek Cogan , Donghong Amy Gao , Alexander Heim-Riether , Eugene Richard Hickey , Matthew Russell Netherton , Philip Dean Ramsden , David Charles Thompson , Zhaoming Xiong
- Applicant: Michael J. Burke , Derek Cogan , Donghong Amy Gao , Alexander Heim-Riether , Eugene Richard Hickey , Matthew Russell Netherton , Philip Dean Ramsden , David Charles Thompson , Zhaoming Xiong
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Anthony P. Bottino
- International Application: PCT/US2011/026905 WO 20110302
- International Announcement: WO2011/109470 WO 20110909
- Main IPC: A61K31/4164
- IPC: A61K31/4164 ; A61K31/4192 ; C07D249/04 ; C07D247/02 ; C07D257/04
Abstract:
Disclosed are Cathepsin-S reversible inhibitor compounds of the formula (I) which are useful in the treatment of autoimmune and other diseases. Also disclosed are pharmaceutical compositions containing the same, and methods of making and using the same.
Public/Granted literature
- US20130158018A1 Heteroaryl Nitrile Compounds Useful as Inhibitors of Cathepsin-S Public/Granted day:2013-06-20
Information query
