Invention Grant
US08729305B2 Process for the preparation of and crystalline forms of optical enantiomers of modafinil 有权
莫达非尼的光学对映异构体的制备和结晶形式的方法

  • Patent Title: Process for the preparation of and crystalline forms of optical enantiomers of modafinil
  • Patent Title (中): 莫达非尼的光学对映异构体的制备和结晶形式的方法
  • Application No.: US13858483
    Application Date: 2013-04-08
  • Publication No.: US08729305B2
    Publication Date: 2014-05-20
  • Inventor: Pierre LeproustOlivier Neckebrock
  • Applicant: Teva Sante
  • Applicant Address: FR La Defense Cedex (Paris)
  • Assignee: Teva Sante
  • Current Assignee: Teva Sante
  • Current Assignee Address: FR La Defense Cedex (Paris)
  • Priority: FR0216412 20021220
  • Main IPC: C07C317/28
  • IPC: C07C317/28 C07C233/05 A61K31/165
Process for the preparation of and crystalline forms of optical enantiomers of modafinil
Abstract:
The invention relates to a polymorphic form of (−)-modafinil that produces a powder X-ray diffraction spectrum comprising intensity peaks corresponding to interplanar spacings of about 14.14, 10.66, 7.80 and 4.02 Å, and a process for the preparation thereof.
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