Invention Grant
US08729305B2 Process for the preparation of and crystalline forms of optical enantiomers of modafinil
有权
莫达非尼的光学对映异构体的制备和结晶形式的方法
- Patent Title: Process for the preparation of and crystalline forms of optical enantiomers of modafinil
- Patent Title (中): 莫达非尼的光学对映异构体的制备和结晶形式的方法
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Application No.: US13858483Application Date: 2013-04-08
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Publication No.: US08729305B2Publication Date: 2014-05-20
- Inventor: Pierre Leproust , Olivier Neckebrock
- Applicant: Teva Sante
- Applicant Address: FR La Defense Cedex (Paris)
- Assignee: Teva Sante
- Current Assignee: Teva Sante
- Current Assignee Address: FR La Defense Cedex (Paris)
- Priority: FR0216412 20021220
- Main IPC: C07C317/28
- IPC: C07C317/28 ; C07C233/05 ; A61K31/165

Abstract:
The invention relates to a polymorphic form of (−)-modafinil that produces a powder X-ray diffraction spectrum comprising intensity peaks corresponding to interplanar spacings of about 14.14, 10.66, 7.80 and 4.02 Å, and a process for the preparation thereof.
Public/Granted literature
- US20130274521A1 PROCESS FOR THE PREPARATION OF AND CRYSTALLINE FORMS OF OPTICAL ENANTIOMERS OF MODAFINIL Public/Granted day:2013-10-17
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