A method and device for controlling power of an active matrix organic light-emitting diode are provided. The method for controlling power of an active matrix organic light-emitting diode includes: calculating a frame data rate, which is a ratio of a light emitting pixel quantity representing a specific color in an image data to be displayed; determining a luminance reducing amount mapped to the frame data rate; and controlling and displaying an entire luminance of an image according to the luminance reducing amount.