A power amplifier power controller in the power amplifier system monitors various operating conditions of the power amplifier, and controls the output transmit power of the power amplifier by coordinated control of both the input drive level to the power amplifier and the gain of the power amplifier. The power amplifier power controller controls the input drive level to the power amplifier so that the input drive level does not change substantially while adjusting the gain of the power amplifier to maximize the transmit power. The power amplifier power controller may also adjust the input drive level by some portion of the overall change required to the power of the power amplifier, while adjusting the gain of the power amplifier by the remaining portion of such overall change.