A web-based hierarchical temporal memory (HTM) system in which one or more client devices communicate with a remote server via a communication network. The remote server includes at least a HTM server for implementing a hierarchical temporal memory (HTM). The client devices generate input data including patterns and sequences, and send the input data to the remote server for processing. The remote server (specifically, the HTM server) performs processing in order to determine the causes of the input data, and sends the results of this processing to the client devices. The client devices need not have processing and/or storage capability for running the HTM but may nevertheless take advantage of the HTM by submitting a request to the HTM server.