Embodiments of the present invention execute an anti-prefetch instruction. These embodiments start by decoding instructions in a decode unit in a processor to prepare the instructions for execution. Upon decoding an anti-prefetch instruction, these embodiments stall the decode unit to prevent decoding subsequent instructions. These embodiments then execute the anti-prefetch instruction, wherein executing the anti-prefetch instruction involves: (1) sending a prefetch request for a cache line in an L1 cache; (2) determining if the prefetch request hits in the L1 cache; (3) if the prefetch request hits in the L1 cache, determining if the cache line contains a predetermined value; and (4) conditionally performing subsequent operations based on whether the prefetch request hits in the L1 cache or the value of the data in the cache line.