Invention Grant
- Patent Title: Perfluorocarbon nano-emulsion containing quantum dot nanoparticles and method for preparing the same
- Patent Title (中): 含有量子点纳米粒子的全氟化碳纳米乳液及其制备方法
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Application No.: US12738394Application Date: 2008-08-20
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Publication No.: US08734762B2Publication Date: 2014-05-27
- Inventor: Bong Hyun Chung , Yong Taik Lim , Bang Sil Choi , Jung Hyun Han
- Applicant: Bong Hyun Chung , Yong Taik Lim , Bang Sil Choi , Jung Hyun Han
- Applicant Address: KR Daejeon
- Assignee: Korea Research Institute of Bioscience and Biotechnology
- Current Assignee: Korea Research Institute of Bioscience and Biotechnology
- Current Assignee Address: KR Daejeon
- Agency: Moore & Van Allen, PLLC
- Agent Tristan A. Fuierer
- Priority: KR10-2007-0105083 20071018
- International Application: PCT/KR2008/004821 WO 20080820
- International Announcement: WO2009/051337 WO 20090423
- Main IPC: A61B5/00
- IPC: A61B5/00 ; A61B8/00 ; A61K9/66

Abstract:
The present invention relates to a perfluorocarbon nanoemulsion containing quantum dot nanoparticles and a method for preparing the same, more specifically, relates to a method for preparing a multifunctional perfluorocarbon nanoemulsion which simultaneously shows the fluorine-based magnetic resonance properties of perfluorocarbon and the optical properties of quantum dot nanoparticles, the method comprising dispersing quantum dot nanoparticles, modified with a fluorine end group, in perfluorocarbon, and then adding an aqueous emulsifier solution containing lipid to the dispersion. The disclosed perfluorocarbon nanoemulsion containing quantum dot nanoparticles has excellent biocompatibility and simultaneously shows optical properties and magnetic resonance properties, and thus can be used as a contrast agent for multi-mode molecular imaging. Accordingly, the nanoemulsion can be used to study cell and small-animal molecular imaging in various fields, including biological and medical fields.
Public/Granted literature
- US20100233094A1 PERFLUOROCARBON NANO-EMULSION CONTAINING QUANTUM DOT NANOPARTICLES AND METHOD FOR PREPARING THE SAME Public/Granted day:2010-09-16
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