Invention Grant
- Patent Title: Mutants of IL-29
- Patent Title (中): IL-29突变体
-
Application No.: US13687851Application Date: 2012-11-28
-
Publication No.: US08734776B2Publication Date: 2014-05-27
- Inventor: Lowell J. Brady , Kevin M. Klucher , Chung Chan , Dennis L. Dong , Hong Y. Liu , Paul O. Sheppard , Thomas R. Bukowski
- Applicant: ZymoGenetics, Inc.
- Applicant Address: US WA Seattle
- Assignee: ZymoGenetics, Inc.
- Current Assignee: ZymoGenetics, Inc.
- Current Assignee Address: US WA Seattle
- Agent Bing Hai
- Main IPC: A61K38/19
- IPC: A61K38/19 ; C07K14/54 ; A61K45/00
Abstract:
Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.
Public/Granted literature
- US20130089517A1 HOMOGENEOUS PREPARATIONS OF IL-28 AND IL-29 Public/Granted day:2013-04-11
Information query
IPC分类:
