Invention Grant
US08734813B2 Multivalent meningococcal polysaccharide-protein conjugate vaccine
有权
多发性脑膜炎球菌多糖 - 蛋白质结合疫苗
- Patent Title: Multivalent meningococcal polysaccharide-protein conjugate vaccine
- Patent Title (中): 多发性脑膜炎球菌多糖 - 蛋白质结合疫苗
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Application No.: US13843037Application Date: 2013-03-15
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Publication No.: US08734813B2Publication Date: 2014-05-27
- Inventor: Robert P. Ryall
- Applicant: Sanofi Pasteur Inc.
- Applicant Address: US PA Swiftwater
- Assignee: Sanofi Pasteur, Inc.
- Current Assignee: Sanofi Pasteur, Inc.
- Current Assignee Address: US PA Swiftwater
- Agency: Pierce Atwood, LLP
- Agent Raymond G. Arner
- Main IPC: A61K39/095
- IPC: A61K39/095 ; A61K39/385 ; A61K39/02 ; A61K39/00 ; A01N43/04 ; C07H1/00
Abstract:
The present invention describes a combined vaccine that offers broad protection against meningococcal disease caused by the pathogenic bacteria Neisseria meningitidis. The vaccine is comprised of four distinct polysaccharide-protein conjugates that are formulated as a single dose of vaccine. Purified capsular polysaccharides from Neisseria meningitidis serogroups A, C, W-135, and Y are chemically activated and selectively attached to a carrier protein by means of a covalent chemical bond, forming polysaccharide-protein conjugates capable of eliciting long-lasting immunity to a variety of N. meningitidis strains in children as well as adults.
Public/Granted literature
- US20130216571A1 Multivalent Meningococcal Polysaccharide-Protein Conjugate Vaccine Public/Granted day:2013-08-22
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