Invention Grant
US08734825B2 Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens 有权
将水溶性或水不溶性治疗剂局部输送到体腔表面

  • Patent Title: Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
  • Patent Title (中): 将水溶性或水不溶性治疗剂局部输送到体腔表面
  • Application No.: US13919443
    Application Date: 2013-06-17
  • Publication No.: US08734825B2
    Publication Date: 2014-05-27
  • Inventor: Eugene T. MichalMatthew J. Pollman
  • Applicant: Covidien LP
  • Applicant Address: US MA Mansfield
  • Assignee: Covidien LP
  • Current Assignee: Covidien LP
  • Current Assignee Address: US MA Mansfield
  • Agent Alana T. Bergman, Esq.
  • Main IPC: A61F13/00
  • IPC: A61F13/00 A61L29/08 A61L29/16 A61M25/10
Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
Abstract:
A method and device for local delivery of a water-insoluble therapeutic agent to the tissue of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with a non-durable coating which comprises poly(HEMA) complexed with iodine and has a substantially water-insoluble therapeutic agent dispersed therein. The medical disposable device is inserted into a body lumen, and expanded to contact the non-durable coating against the body lumen and deliver the substantially water-insoluble therapeutic agent to the body lumen tissue.
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