Invention Grant
- Patent Title: Methods for targetted mutagenesis in gram-positive bacteria
- Patent Title (中): 革兰氏阳性菌靶向诱变方法
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Application No.: US12233806Application Date: 2008-09-19
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Publication No.: US08735160B2Publication Date: 2014-05-27
- Inventor: Yunfeng Yang
- Applicant: Yunfeng Yang
- Applicant Address: US TN Oak Ridge
- Assignee: UT-Battelle, LLC
- Current Assignee: UT-Battelle, LLC
- Current Assignee Address: US TN Oak Ridge
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12N15/87
Abstract:
The present invention provides a method of targeted mutagenesis in Gram-positive bacteria. In particular, the present invention provides a method that effectively integrates a suicide integrative vector into a target gene in the chromosome of a Gram-positive bacterium, resulting in inactivation of the target gene.
Public/Granted literature
- US20100075303A1 METHODS FOR TARGETTED MUTAGENESIS IN GRAM-POSITIVE BACTERIA Public/Granted day:2010-03-25
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