Invention Grant
US08735351B2 Phospholipid-enriched vesicles bearing tissue factor having haemostatic activities and uses thereof
有权
富含磷脂的囊泡带有具有止血活性的组织因子及其用途
- Patent Title: Phospholipid-enriched vesicles bearing tissue factor having haemostatic activities and uses thereof
- Patent Title (中): 富含磷脂的囊泡带有具有止血活性的组织因子及其用途
-
Application No.: US13642491Application Date: 2011-04-19
-
Publication No.: US08735351B2Publication Date: 2014-05-27
- Inventor: Jesús Murat Moreno , Juan Ramon Rodriguez Fernández-Alba
- Applicant: Jesús Murat Moreno , Juan Ramon Rodriguez Fernández-Alba
- Applicant Address: ES Barcelona
- Assignee: Thrombotargets Europe, S.L.
- Current Assignee: Thrombotargets Europe, S.L.
- Current Assignee Address: ES Barcelona
- Agency: Hamilton, DeSanctis and Cha, LLP.
- Agent Peter B. Scull
- Priority: EP10382085 20100419
- International Application: PCT/EP2011/056219 WO 20110419
- International Announcement: WO2011/131658 WO 20111027
- Main IPC: A61K38/36
- IPC: A61K38/36 ; A61P9/00 ; G01N33/86
Abstract:
The invention relates to a method for improving the procoagulant properties of TF expressed in eukaryotic cells by contacting microvesicles derived from said eukaryotic cells with a negatively-charged phospholipid such as phosphatidylserine. The invention also relates to microvesicles obtained using said method as well as to the uses thereof as procoagulant agents, for wound healing and for promoting angiogenesis.
Public/Granted literature
- US20130059782A1 PHOSPHOLIPID-ENRICHED VESICLES BEARING TISSUE FACTOR HAVING HAEMOSTATIC ACTIVITIES AND USES THEREOF Public/Granted day:2013-03-07
Information query
IPC分类:
