Invention Grant
- Patent Title: Combinations of modalities for the treatment of diabetes
- Patent Title (中): 糖尿病治疗方式的组合
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Application No.: US13534571Application Date: 2012-06-27
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Publication No.: US08735359B2Publication Date: 2014-05-27
- Inventor: Tihamer Orban
- Applicant: Tihamer Orban
- Applicant Address: US MA Brookline
- Assignee: Orban Biotech LLC
- Current Assignee: Orban Biotech LLC
- Current Assignee Address: US MA Brookline
- Agency: Nutter McClennen & Fish LLP
- Agent John J Penny, Jr.; Isaac A. Hubner
- Main IPC: A61K38/28
- IPC: A61K38/28 ; A61K39/395 ; A61K38/16 ; A61K38/17 ; A61K39/00 ; C07K14/62 ; C07K14/47 ; C07K14/705
Abstract:
A method of treating, preventing, or delaying the progression of Type 1 diabetes mellitus by administering an effective amount of a fusion protein composition comprising a T-cell co-stimulation antagonist and a portion of an immunoglobulin molecule and an effective amount of a Type 1 diabetes autoantigen. The method includes, for example, administering a cytotoxic T-lymphocyte-associated antigen 4 (CTLA4) molecule and a Type 1 diabetes autoantigen. Pharmaceutical compositions are also provided herewith.
Public/Granted literature
- US20130315904A1 COMBINATIONS OF MODALITIES FOR THE TREATMENT OF DIABETES Public/Granted day:2013-11-28
Information query
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