Invention Grant
US08735368B2 Antisense oligonucleotides against cPLA2, compositions and uses thereof
有权
针对cPLA2的反义寡核苷酸，其组合物和用途
- Patent Title: Antisense oligonucleotides against cPLA2, compositions and uses thereof
- Patent Title (中): 针对cPLA2的反义寡核苷酸，其组合物和用途
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Application No.: US13547113Application Date: 2012-07-12
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Publication No.: US08735368B2Publication Date: 2014-05-27
- Inventor: Rachel Levy
- Applicant: Rachel Levy
- Applicant Address: IL Tel-Aviv IL Beer-Sheva
- Assignee: Mor Research Applications Ltd.,Ben-Gurion University of the Negev Research and Development Authority
- Current Assignee: Mor Research Applications Ltd.,Ben-Gurion University of the Negev Research and Development Authority
- Current Assignee Address: IL Tel-Aviv IL Beer-Sheva
- Priority: IL161579 20040422
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C07H21/04
Abstract:
Antisense oligonucleotides against cPLA2 are provided, which are capable of inhibiting cPLA2 expression as well as superoxide production, especially in phagocytes. These antisense oligonucleotides are powerful agents for the treatment of inflammatory conditions, in particular arthritis, as well as in neurodegenerative diseases. The antisense oligonucleotides or compositions comprising the same may be used in methods of treatment of such diseases.
Public/Granted literature
- US20120277292A1 ANTISENSE OLIGONUCLEOTIDES AGAINST cPLA2, COMPOSITIONS AND USES THEREOF Public/Granted day:2012-11-01
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