Invention Grant
- Patent Title: Carbonate prodrugs and methods of using the same
- Patent Title (中): 碳酸酯前药及其使用方法
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Application No.: US12993089Application Date: 2009-05-20
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Publication No.: US08735376B2Publication Date: 2014-05-27
- Inventor: Naweed Muhammad , Keith R. Bley
- Applicant: Naweed Muhammad , Keith R. Bley
- Applicant Address: US NY Ardsley
- Assignee: Acorda Therapeutics, Inc.
- Current Assignee: Acorda Therapeutics, Inc.
- Current Assignee Address: US NY Ardsley
- Agency: Morrison & Foerster LLP
- International Application: PCT/US2009/044746 WO 20090520
- International Announcement: WO2009/143297 WO 20091126
- Main IPC: A61K31/664
- IPC: A61K31/664 ; C07F9/06
Abstract:
The present invention provides carbonate prodrugs which comprise a carbonic phosphoric anhydride prodrug moiety attached to the hydroxyl or carboxyl group of a parent drug moiety. The prodrugs may provide improved physicochemical properties over the parent drug. Also provided are methods of treating a disease or condition that is responsive to the parent drug using the carbonate prodrugs, as well as kits and unit dosages.
Public/Granted literature
- US20110212927A1 CARBONATE PRODRUGS AND METHODS OF USING THE SAME Public/Granted day:2011-09-01
Information query
