Invention Grant
US08735418B2 Pyrimidine-2-amine compounds and their use as inhibitors of JAK kinases
有权
嘧啶-2-胺化合物及其作为JAK激酶抑制剂的用途
- Patent Title: Pyrimidine-2-amine compounds and their use as inhibitors of JAK kinases
- Patent Title (中): 嘧啶-2-胺化合物及其作为JAK激酶抑制剂的用途
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Application No.: US13619843Application Date: 2012-09-14
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Publication No.: US08735418B2Publication Date: 2014-05-27
- Inventor: Somasekhar Bhamidipati , Jeffrey Clough , Ankush Argade , Rajinder Singh , Vadim Markovtosov , Pingyu Ding , Jiaxin Yu , Andy Atuegbu , Hui Hong , Ihab Darwish , Sambiah Thota
- Applicant: Somasekhar Bhamidipati , Jeffrey Clough , Ankush Argade , Rajinder Singh , Vadim Markovtosov , Pingyu Ding , Jiaxin Yu , Andy Atuegbu , Hui Hong , Ihab Darwish , Sambiah Thota
- Applicant Address: US CA South San Francisco
- Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Seed IP Law Group PLLC
- Agent Travis Young
- Main IPC: A61K31/505
- IPC: A61K31/505 ; A61K31/506
Abstract:
This invention is directed to compounds of formula (I): where n, m, Y, R1, R2, R3, R4 and R5 are disclosed herein, as isolated stereoisomers or mixtures thereof, or pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising the compounds of formula (I); and methods of using the compounds and the pharmaceutical compositions in treating diseases or conditions associated with JAK2 activity.
Public/Granted literature
- US20130018041A1 PYRIMIDINE-2-AMINE COMPOUNDS AND THEIR USE AS INHIBITORS OF JAK KINASES Public/Granted day:2013-01-17
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