Invention Grant
US08735444B2 Fluorinated rhodamines as photostable fluorescent dyes for labelling and imaging techniques
有权
氟化罗丹明作为用于标记和成像技术的光稳定荧光染料
- Patent Title: Fluorinated rhodamines as photostable fluorescent dyes for labelling and imaging techniques
- Patent Title (中): 氟化罗丹明作为用于标记和成像技术的光稳定荧光染料
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Application No.: US13380148Application Date: 2009-06-26
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Publication No.: US08735444B2Publication Date: 2014-05-27
- Inventor: Stefan W. Hell , Vladimir N. Belov , Gyuzel Mitronova , Mariano Bossi , Gael Moneron , Christian A. Wurm , Stefan Jakobs , Christian Eggeling , Jakob Bierwagen , Lars Meyer
- Applicant: Stefan W. Hell , Vladimir N. Belov , Gyuzel Mitronova , Mariano Bossi , Gael Moneron , Christian A. Wurm , Stefan Jakobs , Christian Eggeling , Jakob Bierwagen , Lars Meyer
- Applicant Address: DE Munich
- Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
- Current Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
- Current Assignee Address: DE Munich
- Agency: Caesar, Rivise, Bernstein, Cohen & Pokotilow, Ltd.
- International Application: PCT/EP2009/004650 WO 20090626
- International Announcement: WO2010/149190 WO 20101229
- Main IPC: A61K31/352
- IPC: A61K31/352 ; C07D311/82
Abstract:
The present invention relates to novel fluorinated 3,6-diaminoxanthene compounds derived from the basic structural formula (I) and to their uses as photostable fluorescent dyes, e.g. for immunostainings and spectroscopic and microscopic applications, in particular in conventional microscopy, stimulated emission depletion (STED) reversible saturable optically linear fluorescent transitions (RESOLFT) microscopy, and fluorescence correlation spectroscopy. The claimed compounds are also useful as molecular probes in various spectroscopic applications.
Public/Granted literature
- US20120135459A1 NOVEL FLUORINATED RHODAMINES AS PHOTOSTABLE FLUORESCENT DYES FOR LABELLING AND IMAGING TECHNIQUES Public/Granted day:2012-05-31
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